ONCOGEN services!
Oncogen® provides you a fast high quality service in high-definition SNP cancer genotyping.
SNP cancer genotyping with OncoGen will permit you to caracterize many aspects of cancer genome :
- Perform a genome-wide tumoral allelotyping
- Identify amplified chromosomal regions (amplicons) and genic amplifications
- Identific numerical chromosomal anomalies as monosomies, trisomies, tetrasomies
- Identify genomic insertions, deletions and copy number changes at ultra-high resolution
- Stock your data in a powerful dedicated database
- Access Oncobase, a original database in Oncogenetics
- SNPs genotyping
This array-based SNP genotyping method permits to analyze and visualize DNA copy number changes and to accurately characterize loss of heterozygosity (LOH).
It provides highly informative molecular insights on cancer development and progression.
Illumina genotyping data generated with Infinium-based BeadChips or GoldenGate genotyping products can be used to view LOH and copy number information. The BeadStudioTM Genotyping Module software incorporates the ability to analyze genotypes, copy number changes and LOH.
The use of genotyping arrays to measure chromosomal aberrations offers a number of advantages over conventional array CGH (comparative genomic hybridization) methods. For example, array CGH methods are unable to detect LOH since they don’t query genomic DNA on an allele-specific basis.
